Program
Venue: Van Swieten Hall of the Medical University of Vienna
Address: Van Swieten – Gasse 1a, 1090 Vienna (see here on the map).
The program starts in the morning of April, 28th, and ends in the afternoon of April, 29th, with an award ceremony for the best posters, for the best selected talk and for the travel grant awardees.
You can also download the program here.
Thursday, 28 April 2022
| 08:00-09:00 | Registration and poster setup |
| 09:00-09:15 | Introduction by the organizers |
| SESSION 1 | Proteomics and Molecular Tools |
| 09:15-09:45 | Ilaria Piazza, Max-Delbrück-Center for Molecular Medicine, Berlin |
| Protein structures in context with proteome-wide biophysics | |
| 09:45-10:00 | Tycho Mevissen, HHMI and Harvard Medical School, Boston |
| Cell-free Trim-Away reveals the mechanism of TRIM21-mediated targeted protein degradation | |
| 10:00-10:30 | Kathrin Lang, ETH Zürich |
| Genetic code expansion tools for deciphering the ubiquitin code | |
| 10:30-11:00 | Coffee break |
SESSION 2 | Protein Structure and Quality Control |
| 11:00-11:30 | Susan Shao, Harvard Medical School |
| Mechanisms of client selection during protein quality control | |
| 11:30-11:45 | Natalia Szenkier, Weizmann Institute, Rehovot |
| A cysteine tweezer, oxidative switch, regulates proteasome disassembly | |
| 11:45-12:30 | Flash talks 1 – odd poster numbers |
| 12:30-13:50 | Lunch with poster session 1 (odd numbers) |
| 13:50-14:00 | Group photo |
| 14:00-14:30 | Liz Miller, MRC laboratory of Molecular Biology, Cambridge |
| Translational tuning in response to protein folding and secretion defects | |
| 14:30-14:45 | Lisa Merklinger, Technical University of Denmark, Lyngby |
| Phospholipids alter activity and stability of the mitochondrial membrane-bound ubiquitin ligase MARCH5 |
| SESSION 3 | Cellular Homeostasis |
| 14:45-15:15 | Francesco Licausi, University of Oxford |
| A conserved O2 sensing mechanism for eukaryotes based on the N-degron pathway for proteolysis | |
| 15:15-15:30 | Sebastian Guzman Perez, Jagiellonian University, Cracow |
| How an ancient Ubiquitin-like protein delivers sulfur to tRNAs and protects the Proteome | |
| 15:30-16:00 | Coffee break |
| 16:00-16:30 | Michael Rape, UC Berkeley |
| Controlling the cell’s powerhouse: the reductive stress response | |
| 16:30-16:45 | Itika Saha, Max Planck Institute of Biochemistry, Martinsried |
| The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds | |
| 16:45-17:15 | Flash talks 2 – even poster numbers |
| 17:15-19:00 | Wine Reception sponsored by Proxygen with poster session 2 |
| 19:15 | Conference dinner at Stiegl Ambulanz |
Friday, 29 April 2022
| SESSION 4 | Protein Degradation Therapeutics |
| 09:00-09:30 | Eric Fischer,Dana-Farber Cancer Institute, Harvard |
| Hijacking the Ubiquitin System for Protein Degradation Therapeutics | |
| 09:30-09:45 | Francesca Morreale, IMP, Vienna |
| BacPROTACs mediate targeted protein degradation in bacteria | |
| 09:45-10:15 | Mikolaj Slabicki, Dana-Farber Cancer Institute, Harvard |
| Drug-induced polymerization | |
| 10:15-10:30 | Bryony Kennedy, Queen’s University, Belfast |
| The inhibition of the E3 ligase HUWE1 using small molecule inhibitors in multiple myeloma | |
| 10:30-11:00 | Coffee break |
| SESSION 5 | Autophagy |
| 11:00-11:30 | Nobuo Noda, Hokkaido University, Sapporo |
| Regulation of autophagic membrane dynamics by Atg8 lipidation system | |
| 11:30-11:45 | Marion Clavel, GMI, Vienna |
| Cellular cleanup by the autophagy pathway promotes organismal survival during infection by multiple viruses | |
| 11:45-12:00 | Jia Xuan Leong, ZMBP University of Tübingen |
| Battle between bacterial effector and plant autophagy | |
| 12:00-13:00 | Lunch break |
| SESSION 6 | DNA Repair |
| 13:00-13:30 | Helen Walden, University of Glasgow |
| Structural basis of FANCD2 deubiquitination by USP1-UAF1 | |
| 13:30-13:45 | Tamara Sijacki, MRC Laboratory of Molecular Biology, Cambridge |
| Phosphorylation primes FANCD2-FANCI for ubiquitination to activate DNA crosslink repair | |
| 13:45-14:15 | Jesper Svejstrup, University of Copenhagen |
| The Last Resort Pathway for Contending with Transcription-Obstructing DNA Damage | |
| 14:15 | Award ceremony and closing remarks |