Venue: Van Swieten Hall of the Medical University of Vienna

Address: Van Swieten – Gasse 1a, 1090 Vienna (see here on the map).

The program starts in the morning of April, 28th, and ends in the afternoon of April, 29th, with an award ceremony for the best posters, for the best selected talk and for the travel grant awardees. 

You can also download the program here.

Thursday, 28 April 2022

08:00-09:00 Registration and poster setup
09:00-09:15 Introduction by the organizers


Proteomics and Molecular Tools

09:15-09:45 Ilaria Piazza, Max-Delbrück-Center for Molecular Medicine, Berlin
  Protein structures in context with proteome-wide biophysics
09:45-10:00 Tycho Mevissen, HHMI and Harvard Medical School, Boston
Cell-free Trim-Away reveals the mechanism of TRIM21-mediated targeted protein degradation
10:00-10:30 Kathrin Lang, ETH Zürich
  Genetic code expansion tools for deciphering the ubiquitin code
10:30-11:00 Coffee break


Protein Structure and Quality Control

11:00-11:30 Susan Shao, Harvard Medical School
  Mechanisms of client selection during protein quality control
11:30-11:45 Natalia Szenkier, Weizmann Institute, Rehovot
A cysteine tweezer, oxidative switch, regulates proteasome disassembly
11:45-12:30 Flash talks 1 – odd poster numbers


Lunch with poster session 1 (odd numbers)


Group photo
14:00-14:30 Liz Miller, MRC laboratory of Molecular Biology, Cambridge
  Translational tuning in response to protein folding and secretion defects
14:30-14:45 Lisa Merklinger, Technical University of Denmark, Lyngby
Phospholipids alter activity and stability of the mitochondrial membrane-bound ubiquitin ligase MARCH5


Cellular Homeostasis

14:45-15:15 Francesco Licausi, University of Oxford
  A conserved O2 sensing mechanism for eukaryotes based on the N-degron pathway for proteolysis
15:15-15:30 Sebastian Guzman Perez, Jagiellonian University, Cracow
How an ancient Ubiquitin-like protein delivers sulfur to tRNAs and protects the Proteome  
15:30-16:00 Coffee break
16:00-16:30 Michael Rape, UC Berkeley
  Controlling the cell’s powerhouse: the reductive stress response
16:30-16:45 Itika Saha, Max Planck Institute of Biochemistry, Martinsried
The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds
16:45-17:15 Flash talks 2 – even poster numbers


Wine Reception sponsored by Proxygen with poster session 2


Conference dinner at Stiegl Ambulanz

Friday, 29 April 2022


Protein Degradation Therapeutics

09:00-09:30 Eric Fischer,Dana-Farber Cancer Institute, Harvard
  Hijacking the Ubiquitin System for Protein Degradation Therapeutics
09:30-09:45 Francesca Morreale, IMP, Vienna
BacPROTACs mediate targeted protein degradation in bacteria
09:45-10:15 Mikolaj Slabicki, Dana-Farber Cancer Institute, Harvard
  Drug-induced polymerization
10:15-10:30Bryony Kennedy, Queen’s University, Belfast
The inhibition of the E3 ligase HUWE1 using small molecule inhibitors in multiple myeloma
10:30-11:00 Coffee break



11:00-11:30 Nobuo Noda, Hokkaido University, Sapporo
  Regulation of autophagic membrane dynamics by Atg8 lipidation system
11:30-11:45 Marion Clavel, GMI, Vienna
Cellular cleanup by the autophagy pathway promotes organismal survival during infection by multiple viruses
11:45-12:00 Jia Xuan Leong, ZMBP University of Tübingen
Battle between bacterial effector and plant autophagy

Lunch break


DNA Repair

13:00-13:30 Helen Walden, University of Glasgow
  Structural basis of FANCD2 deubiquitination by USP1-UAF1
13:30-13:45 Tamara Sijacki, MRC Laboratory of Molecular Biology, Cambridge
Phosphorylation primes FANCD2-FANCI for ubiquitination to activate DNA crosslink repair
13:45-14:15 Jesper Svejstrup, University of Copenhagen
  The Last Resort Pathway for Contending with Transcription-Obstructing DNA Damage
14:15 Award ceremony and closing remarks