June 10, 2020

Four outstanding scientists have joined our Scientific Advisory Board

We are honored and proud to announce that four outstanding scientists – Judith Frydman (Stanford University), Ramanujan Hegde (MRC-LMB), Noboru Mizushima (University of Tokyo) and Hidde Ploegh (Harvard Medical School) – have accepted our invitation to serve on our Scientific Advisory Board.


Judith Frydman is the Donald Kennedy Chair in Humanities and Sciences and a professor in the Departments of Biology and Genetics at Stanford University. Her lab has made seminal contributions to understand how eukaryotic cells manage their proteome and maintain protein homeostasis (proteostasis). Her studies have important applications to ameliorate aging, neurodegenerative diseases and other misfolding-linked maladies and enable strategies for the treatment of infectious disease and neurodegenerative diseases.


Ramanujan Hegde is a group leader and Joint Head of the Cell Biology Division at the MRC Laboratory of Molecular Biology in Cambridge, UK. Research in the Hegde lab focuses on the biogenesis of membrane proteins and the various quality control pathways that deal with failed protein maturation. Ramanujan Hegde is an elected member of EMBO and a Fellow of the Royal Society.


Noboru Mizushima graduated from the Faculty of Medicine at Tokyo Medical and Dental University in 1991 and received his Ph.D. in 1996. He then moved to the National Institute for Basic Biology and started works on autophagy in yeast and mammals in Dr. Yoshinori Ohsumi’s laboratory. He moved to the Tokyo Metropolitan Institute of Medical Science in 2004 as a laboratory head and was promoted to Professor of Biochemistry and Molecular Biology at the University of Tokyo in 2012. His current research focuses include the physiological roles and molecular mechanisms of autophagy and other intracellular protein/organelle degradation.


Hidde Ploegh obtained his Master of Science degree in biology and chemistry in 1977 from the University of Groningen, and pursued his Ph.D. studies in the lab of Jack Strominger. He received a doctorate from the University of Leiden. He has worked at the University of Cologne, the Netherlands Cancer Institute, Utrecht University, and Harvard Medical School, and is a member of the Whitehead Institute. Hidde Ploegh is member of EMBO and of the National Academy of Sciences.


We are very much looking forward to discussing our projects in Targeted Protein Degradation with them and to obtaining their advice.